Wesley Memorial began at a house in an area just outside of Chattanooga,Tennessee, and in 2019 celebrates 75 years of ministry as a church. The members were committed to sharing the Gospel of Jesus Christ with all around them.

A community grew up around Wesley Memorial and the church became the center of activity there.

Among former Pastors of Wesley Memorial are two who later became United Methodist Bishops and several who were District Superintendents in the Holston Conference of the United Methodist Church.